• Too Much of a Hormone Commonly Used in IVF Decreases the Chances of Success, Study Found

    "More is better" was the popular opinion for this hormone. This study might change that

  • Photo by telmah.hamlet/Flickr

    Considering of conceiving via in vitro fertilization (IVF)? Here’s something you should know: a hormone commonly thought to increase the chances of a woman giving birth via IVF may actually produce the opposite effect.

    Research has found that too much FHS decreases the likelihood of a live birth, contradicting the popular belief that larger amounts of it increases the probability of conceiving. The study was published in the journal Fertility and Sterility.

    FHS, or follicle stimulating hormone, is essential in reproduction. Produced by the pituitary gland, it controls women’s ovaries and men’s testes. “Doctors use FSH to stimulate as many follicles as possible in a woman's ovaries to grow, so a large number of eggs can be recovered for IVF,” said the report

    The study, from the Michigan State University, involved analyzing data from more than 650,000 IVF cycles in women all over the U.S.

    “The study answers the question of whether or not more FSH is detrimental to the survival of the embryo,” said co-author of the study and professor of reproductive physiology James Ireland. “As the dosage of FSH increased, live birth rates decreased by as much as 15 to 20 percent,” he said. 

    What's more, according to Ireland, the research might not only show the contradictory effects of too much FHS but may also provide markers for future research attempting to determin the right dose of FHS to use for IVF.

    More and more babies are being born though IVF in recent times compared to before. This is because IVF has given women with troubles conceiving a better chance at being mothers. A report released earlier this year by the Society for Assisted Reproductive Technology (SART) showed that there were 1,000 more American babies born through IVF in 2013 than in 2012. 

    The fertilization process has even turned a number of virgin women into mothers amounting to at least 25 virgin moms in the past five years, reported the Daily Mail in September. Reasons for opting to raise a child without a partner vary but most are saying they can no longer wait for the right person to come along.

    IVFs success rate varies by age: 41% for women under 35, 32% for ages 35 to 37, and 23% for ages 38 to 40.


    Source:
    Nov. 23, 2015. "Study Counters Long-Time Practice of Prescribing More Fertility Hormones". msutoday.msu.edu

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