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  • There have been no health warnings for pregnant women against this artificial sweetener. However, women with phenylketonuria (PKU), an inherited inborn error of body chemistry, should avoid food and drinks containing aspartame. Phenylalanine, a substance which comprises 50 percent of aspartame, can cause irreversible brain damage and  death, especially when used  in high quantities or during  pregnancy by those with PKU.

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